Herpes
If I had genital herpes, I would kill myself. Dedicate my life to science. Finding an appropriate sexual partner is already so tiresome as it is, imagine, every time, having to disclose that you have lesions on your dick and that you will infect them by participating in the sole activity that makes life worth living. There’s no way it doesn’t “kill the vibe” instantly. And if you don’t say it you’re thinking about it the whole time. These people are fucked. You can only fuck other positives. What kind of life is that.